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Blood Pressure + Endothelial Glycocalyx Support
Next generation cardiovascular formula featuring four clinically studied, plant-based ingredients at clinical strength dosages utilizing our unique SlideTech™ Tablet Coating Technology.
Helps support:
How to Use
Recent research has shown that the polyphenols found in grape seed extracts, most notably proanthocyanidins, can provide many health benefits. In a leading human clinical study, this specific grape seed extract ingredient (standardized to 95% proanthocyanidins) was shown to promote normal blood pressure nearly 2x more effectively than diet and exercise alone.2
The clinically researched fucoidan in glyNOcalyx™ is a highly characterized, certified organic complex of fucoidan and marine polyphenols sourced from Fucus vesiculosus seaweed. This high-purity, potent antioxidant provides a rich source of polysaccharides that help serve as structural building blocks for the glycocalyx.
glyNOcalyx™ features a unique melon juice concentrate, obtained from a proprietary variety of cantaloupe melon exclusively grown in the south of France that provides a naturally rich source of Superoxide Dismutaste (SOD). This enzymatic antioxidant has been found to help protect the glycocalyx and provide structure support.
The endothelial glycocalyx is a micro-thin, sugar-rich layer that has a hair-like resemblance and covers the apical side of vascular endothelial cells, projecting into the lumen of blood vessels. It serves as a protective barrier allowing the blood to flow without impacting the inner wall of the blood vessels. The endothelial cell glycocalyx is negatively charged and heavily hydrated, consisting of a variety of glycosaminoglycans chains such as heparan sulfate and chondroitin sulfate as well as lipoprotein lipase, chemokines and other blood borne proteins.
Important functions of the glycocalyx include:
-Helps repel erythrocytes and protects endothelial cells from shear stress resulting from blood flow
-Limits the adhesion of platelets and leucocytes with the endothelium preventing trans-endothelial migration and chemotaxis
-Binds ligands and enzymes, which facilitate cellular and enzymatic modifications
-Binds enzymes, such as superoxide dismutase, that scavenge free radicals thereby reducing oxidative stress
-Regulates vascular tone by adjusting eNOS activity and nitric oxide production
Direction: As a dietary supplement, take one (1) tablet daily or as directed by your healthcare professional.
Precaution: For adult use only. Consult a physician if are pregnant, nursing, taking medications, or have a medical condition. Keep out of reach of children.
Recent research has shown that certain nutrients, antioxidants, and lifestyle can serve as foundational building blocks to help support a healthy glycocalyx. Targeted ways to support the glycocalyx include:
- Maintain a well-balanced diet
- Supplement with glycosaminoglycans, and sulfated polysaccharides primarily from marine algae
- Reduce oxidative stress and support a healthy inflammatory response with appropriate nutrients
- Supplement with heparinase inhibitors
- Engage in appropriate physical activity
- Support healthy blood pressure
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Every product from humanN is made with the highest quality, clinically researched ingredients that have been rigorously tested and approved by our team of scientists and industry experts
We partner with the most gifted experts in their fields of science, medicine, and nutrition
To Make You, The Best Version of You. Our Products are inspired By The Nobel Prize-Winning Discovery of Nitric Oxide (N-O) for its role as a blood vessel signaling molecule. In fact, we’re the only company in the world that holds an exclusive license to use our patented N-O platform technology. And that’s just the start.
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